- InChI: InChI=1S/C39H60N8O13/c1-4-21(2)32(38(58)47-19-7-9-29(47)37(57)44-27(39(59)60)8-5-6-18-40)46-36(56)28(20-23-10-12-24(48)13-11-23)45-33(53)22(3)42-35(55)26(15-17-31(51)52)43-34(54)25(41)14-16-30(49)50/h10-13,21-22,25-29,32,48H,4-9,14-20,40-41H2,1-3H3,(H,42,55)(H,43,54)(H,44,57)(H,45,53)(H,46,56)(H,49,50)(H,51,52)(H,59,60)/t21-,22-,25-,26-,27-,28-,29-,32-/m0/s1
- Formula: C39H60N8O13
- Molecular Weight: 848.952 g/mol
- Exact mass: 848.428 g/mol
- Monoisotopic mass: 848.428 g/mol
Human Growth Hormone (HGH)
Human Growth hormone (HGH) is a peptide hormone that stimulates growth, cell reproduction and regeneration in humans and other animals. It is a type of mitogen which is specific only to certain kinds of cells. Growth hormone is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. Many factors influence the release of Human Growth Hormone, however, including nutrition and exercise.
The body naturally produces growth hormone (HGH or simply GH) in the pituitary gland, and, as its name implies, it is responsible for cell growth and regeneration. Increasing muscle mass and bone density are impossible without GH, but it also plays a major role in maintaining the health of all human tissue, including that of the brain and other vital organs. When secreted, GH remains active in the bloodstream for only a few minutes, but this is enough time for the liver to convert it into growth factors, the most crucial of which is insulin-like growth factor-1, or IGF-1, which boasts a host of anabolic properties. Scientists began to harvest GH from the pituitary glands of cadavers in the 1950s, but didn’t synthesise the first HGH in laboratories until 1981, with its use as a performance-enhancing drug becoming popular shortly thereafter.
HGH is used in medicine to treat children’s growth disorders and adult growth hormone deficiency. Studies reliably demonstrate that the following are among the beneficial effects of modulating HGH:
- Enhanced Ability to Maintain Proper Body Fat Levels
- A Tighter Physique
- Enhanced Metabolic Rate
- Enhanced Sense of Wellbeing
- Healthier Skin
- Improved Sleeping Patterns
- Increased Bone Strength
- Increased Energy
- Increased Joint Strength
- Increased Lean Tissue Growth (Lean muscle mass)
- Increased Rate of Physical Recovery
- Increased Tendon Strength
- Increased HDL (good) cholesterol
- Increases deiodination of T4 to T3
- Decreased Body Fat – promotes lipolysis
- Decreased LDL (bad) cholesterol
- Decreases liver uptake of glucose
- Decreased recovery time in-between workouts
HGH shows much more effect and positive qualities in stack with a steroid cycle as alone. So, this compound is generally suitable for cutting cycles to get lean muscles and burn fat.
Potential Side Effects:
Overall, Human Growth Hormone is one of the safest hormones any man or woman can administer to their body. This is not a foreign substance, it is a hormone your body is well accustomed to, and more importantly, one it needs. While overall it is a tremendously safe hormone, there are possible side effects of Human Growth Hormone use. The most common side effects of HGH include water retention, specifically around the ankles and wrist, joint pain and headaches. Some may also experience flu like symptoms, but such symptoms normally only exist at the early stages of use and normally subside quickly.
The side effects of HGH can also include carpal tunnel syndrome, which in part is often due to water retention related effects. Such effects are most common among performance level doses of the hormone. Hypothyroidism, a deficiency in thyroid hormone production is also possible, especially with performance level doses. This issue can be remedied by the use of Cytomel (Liothyronine Sodium) or what is commonly referred to as T3. Some may also experience nausea, dizziness, respiratory infection and numbness of the skin. While possible, these side effects of Human Growth Hormone are the least likely with moderate edema, slight joint pain and headaches being the most common.
The side effects of Human Growth Hormone can become very problematic when the hormone is abused. Abuse will refer to extremely high doses; total use can be indefinite and often safe, but the dose must remain reasonable. HGH abuse can lead to enlarged hands, feet and jaw, and more severally to the enlargement of internal organs. The side effects of HGH can also include short-term type-2 diabetes due to the hormone’s ability to increase blood sugar and reduce insulin sensitivity.
The final possible side effect of Human Growth Hormone is an irritated injected area. Small lumps in the skin or an itchy feeling at the injected area are commonplace. You may need to move your injections around to find the most comfortable spot. However, many enjoy injecting their HGH into the same area every time as it is one of the few hormones that have been shown to have spot injection benefits. Injecting repeatedly into the same area has been shown to promote localised lipolysis, which will lead many men to always inject their HGH into the fatty tissue in their stomach.
RECOMMENDED DOSAGE: Human growth hormone is measured in IU (international units) and mg (milligrams). 1 mg equals approximately 3 IU while 1 IU equals approximately 0.33 mg.
The dosage depends on the goal. People generally use 2 IU per day for anti ageing purposes, between 4 to 6 IU for bodybuilding, weight loss and fitness, between 8 to 16 IU is used for short duration to treat severe burns or recover after injuries.